Benign prostatic hyperplasia

Benign prostatic hyperplasia

Benign prostatic hyperplasia is a common disease of older men, that the autopsy information: its incidence increases with age, but not necessarily benign prostatic hyperplasia who have symptoms. A group of foreign statistical information on the autopsy results: men suffering from benign prostatic hyperplasia in the 40-year-old has more than 80.1 percent, over the age of 80 are 90.5 percent. In recent years China reported prostatic hyperplasia rising trend year by year, the incidence rate of 25.7 percent, the incidence rate for urban workers, 30.4%, 21.9% of the farmers. China's incidence of benign prostatic hyperplasia increased, and may be gradually increased the number of ageing-related.
Etiology and pathogenesis of:
BPH-related causes and pathogenesis of many, but the cause has still not clarified. However, symptoms must have benign prostatic hyperplasia
(1) there have testicular
(2) age of two important conditions for growth.
1970 W: ISOM by dihydrotestosterone doctrine should be to: dihydrotestosterone exist in prostate cells, it is the role of 5 a-reductase from the conversion of testosterone from its strong role in the physiology of testosterone, mammals And the dog will only happen benign prostatic hyperplasia, in the event of the prostate hyperplasia in dihydrotestosterone in higher than normal prostate tissue 3-4 times. Therefore dihydrotestosterone trigger more benign prostatic hyperplasia, this theory in the academic community hold a major position, so now that 5 a-reductase inhibitors will become the effective treatment of BPH drugs.
Clinical manifestations:
Subtle early symptoms of benign prostatic hyperplasia, as the condition for the development of early symptoms of the growing number of nocturnal enuresis, each small amount of urine, and then during the day also frequency, urinary tract obstruction next 50 to 80 percent of the patients have urgency and urgent Incontinence. Detrusor decompensated after each urination can not be emptying the bladder urine night, residual urine there, if secondary infection, stones, the frequency and more evident there Niaotong.
When the prostate hyperplasia to the urethra, will lead to outstanding after the urethral extension, bending, narrow, to the sudden proliferation of the bladder neck ball valve can be formed, these changes may cause more resistance increased urination, the patient voiding the slow start time urination Extended range not far from the urine of small and powerless, interrupted urine flow, urine after Ms Lek. When the residual urine in the bladder when the great expansion and excessive pressure can be increased in Chongyi incontinence night enuresis.
Some patients in peacetime but not in residual urine Shouliang, drinking, or other causes Bieniao sympathetic excited when a sudden acute urinary retention. In the bladder neck, prostate glands and coated, smooth muscle is rich in-a-receptor on the kidney, in sympathetic excitement will shrink the prostate gland and increase tension, benign prostatic hyperplasia caused lower urinary tract obstruction in addition to mechanical factors , Is also available in capsule, smooth muscle contraction, the tension increased, and so on.
BPH voiding obstruction often leads to urinary tract infections, there urgency, Niaotong the event of uplink infections can be developed fever, sometimes hematuria, the final secondary bladder stones kidney dysfunction.
BPH diagnosis:
Anus that the most important appointment, benign prostatic hyperplasia is divided into four common Gedan, eggs, Edan, more than Edan big to describe. B-rectal, stomach B-diagnosis. CT, MRI of benign prostatic hyperplasia without significance. Through the flow rate of illness and can grasp the operation time. Because of benign prostatic hyperplasia is an older disease, renal function, heart and lung function checks are also important.